Karin Humphries

Program Head – Cardiovascular Health, D.Sc., M.Sc., MBA, FAHA

After completing undergraduate work in biochemistry and kinesiology, followed by a master’s degree in Experimental Pathology, Dr. Karin Humphries completed her doctoral degree in Epidemiology and Health Services Research at Erasmus University in the Netherlands.

Research Interests

  • Outcomes after coronary revascularization (PCI, CABG)
  • Sex differences in diagnosis, treatment, and outcomes of patients with coronary disease
  • Health services research—evidence-based medication use post-AMI
  • Cardiovascular epidemiology

Her current work is mostly focused on sex and gender differences in the diagnosis, treatment, and outcomes in subjects with coronary artery disease.

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A co-investigator with the GENESIS Team funded under an ICE grant from the Canadian Institutes of Health Research, Dr. Humphries is currently investigating the impact of using sex-specific thresholds in the evaluation of patients presenting to the emergency department (ED) with suspected myocardial ischemia. The CODE-MI trial is examining this question in 30 hospitals, in 8 provinces, across Canada, using a stepped-wedge, cluster-randomized trial, which is funded by CIHR.

She is the Program Head – Cardiovascular Health (ICVHealth) at CHÉOS. The ICVHealth team is working closely with cardiologists and ED physicians to understand the treatment and outcomes of patients experiencing an out-of-hospital cardiac arrest.

Dr. Humphries and has undertaken multiple projects that demonstrate the potential for broad impact by improving patient outcomes and enhancing resource utilization. The FREEDOM Real World study aims to assess the effect of the Future Revascularization Evaluation in Patients with Diabetes Mellitus: Optimal Management of Multi-Vessel Disease (FREEDOM) trial on clinical practice in B.C.

Additional work includes evaluation of outcomes of patients after the percutaneous coronary intervention (PCI) and the impact of a relative increase in PCI compared to coronary artery bypass surgery, which has been observed across Canada. Most of this work is done using clinical data from the B.C. Cardiac Registry, linked to Ministry of Health administrative databases (DAD, MSP, PharmaNet) and Vital Statistics.