Principal Investigator: Dr. John Esdaile (Co-Investigators: Drs. Michal Abrahamowicz, Juan Avina-Zubieta, Cheryl Barnabe, Mary De Vera, Jan Dutz, Gilaad Kaplan, Dianne Lacaille, Linda Li, Carlo Marra)
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This five-year project studies inflammatory skin, joint, and bowel conditions, affecting over five million Canadians. Diseases in this category include psoriasis (skin), rheumatoid arthritis, ankylosing spondylitis, gout, osteoarthritis, lupus and lupus-like diseases (joint), and Crohn’s disease and ulcerative colitis (bowel). Researchers are evaluating the commonality, cause, and impact of complications from these diseases on individuals, measuring financial costs, and determining whether certain factors can increase or eliminate the risk of complications. This comprehensive project will study more than 500,000 Canadians. Dr. Esdaile and CHÉOS Scientist Dr. Linda Li will also develop patient-centred approaches to reduce or eliminate frequency and consequences of complications of these diseases.