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Work in Progress Seminar: Immune vulnerable populations and adverse effects of osteoporosis therapies

October 11, 2017 @ 12:00 pm – 1:00 pm
Hurlburt Auditorium, St. Paul's Hospital
1081 Burrard Street

Shirin Kalyan, PhD
Scientist, CHÉOS
Assistant Professor, Division of Endocrinology, Department of Medicine, UBC

Abstract: Osteoporosis is estimated to affect over 200 million people worldwide; the osteoporosis drug market is valued over $11.4 billion (USD). Postmenopausal women are the largest collective group on therapy — 1 in 3 women and 1 in 4 men over 50 will be diagnosed with bone fragility. Many chronic conditions, such as living with HIV, cystic fibrosis, IBD, and rheumatoid arthritis increase the risk of bone fragility disorders. In this talk, Dr. Kalyan will share some of her research showing how the standard of care for osteoporosis, bisphosphonates, affect immune function and antioxidant capacity in patients and the potential consequence this may have on developing serious adverse drug effects. These data suggest that some of those most in need of osteoporosis medication may also be most vulnerable to its potential risks.

Work in Progress (WiP) presentations take place at St. Paul’s Hospital in the Hurlburt Auditorium on alternating Wednesdays from 12:00–1:00 PM. These seminars provide investigators with an opportunity to present ongoing research, obtain feedback from colleagues and peers, and make new connections for their projects. Talks are open, and a light lunch is served.

View the 2017-2018 WiP schedule.

Health research in the heart of Vancouver